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Rivaroxaban 99% api cas 366789-02-8 

  Category : Chemicals->Pharmaceutical->pharmaceutical

     
Rivaroxaban 99% api cas 366789-02-8
       

  Product Specification
 
  Country  CN

 

    Product Detail
  <p class="MsoNormal">
Chemical&nbsp;Name: Rivaroxaban
</p>
<p class="MsoNormal">
<!--[if !supportLists]-->(S)&nbsp;<!--[endif]-->-Rivaroxaban
</p>
<p class="MsoNormal">
Rivaroxaban Isomer
</p>
<p class="MsoNormal">
BAY 59-7939
</p>
<p class="MsoNormal">
Rivaroxaban<br />
Molecular&nbsp;Formula: C19H18ClN3O5S<br />
Formula&nbsp;Weight: 435.88<br />
CAS&nbsp;No.: 366789-02-8
</p>
<p class="MsoNormal">
<img src="http://i.bosscdn.com/product/6a/21/83/0e7e21c94f34f9d096e05d7852.gif" title="366789-02-8" alt="366789-02-8" width="150" height="189" /><br />
Rivaroxaban&nbsp;is&nbsp;a&nbsp;pure&nbsp;(S)-enantiomer.&nbsp;It&nbsp;is&nbsp;an&nbsp;odorless,&nbsp;non-hygroscopic,&nbsp;white&nbsp;to&nbsp;yellowish&nbsp;powder.&nbsp;Rivaroxaban&nbsp;is&nbsp;only&nbsp;slightly&nbsp;soluble&nbsp;in&nbsp;organic&nbsp;solvents&nbsp;(e.g.,&nbsp;acetone,&nbsp;polyethylene&nbsp;glycol&nbsp;400)&nbsp;and&nbsp;is&nbsp;practically&nbsp;insoluble&nbsp;in&nbsp;water&nbsp;and&nbsp;aqueous&nbsp;media.<br />
In&nbsp;those&nbsp;with&nbsp;non-valvular&nbsp;atrial&nbsp;fibrillation&nbsp;it&nbsp;appears&nbsp;to&nbsp;be&nbsp;as&nbsp;effective&nbsp;as&nbsp;warfarin&nbsp;in&nbsp;preventing&nbsp;nonhemorrhagic&nbsp;strokes&nbsp;and&nbsp;embolic&nbsp;events.[4]&nbsp;Rivaroxaban&nbsp;is&nbsp;associated&nbsp;with&nbsp;lower&nbsp;rates&nbsp;of&nbsp;serious&nbsp;and&nbsp;fatal&nbsp;bleeding&nbsp;events&nbsp;than&nbsp;warfarin&nbsp;though&nbsp;rivaroxaban&nbsp;is&nbsp;associated&nbsp;with&nbsp;higher&nbsp;rates&nbsp;of&nbsp;bleeding&nbsp;in&nbsp;the&nbsp;gastrointestinal&nbsp;tract.<br />
Rivaroxaban&nbsp;is&nbsp;a&nbsp;morpholine&nbsp;and&nbsp;thiophene&nbsp;derivative&nbsp;that&nbsp;functions&nbsp;as&nbsp;a&nbsp;FACTOR&nbsp;XA&nbsp;INHIBITOR&nbsp;and&nbsp;is&nbsp;used&nbsp;in&nbsp;the&nbsp;treatment&nbsp;and&nbsp;prevention&nbsp;of&nbsp;DEEP-VEIN&nbsp;THROMBOSIS&nbsp;and&nbsp;PULMONARY&nbsp;EMBOLISM.&nbsp;It&nbsp;is&nbsp;also&nbsp;used&nbsp;for&nbsp;the&nbsp;prevention&nbsp;of&nbsp;STROKE&nbsp;and&nbsp;systemic&nbsp;embolization&nbsp;in&nbsp;patients&nbsp;with&nbsp;non-valvular&nbsp;ATRIAL&nbsp;FIBRILLATION,&nbsp;and&nbsp;for&nbsp;the&nbsp;prevention&nbsp;of&nbsp;atherothrombotic&nbsp;events&nbsp;in&nbsp;patients&nbsp;after&nbsp;an&nbsp;ACUTE&nbsp;CORONARY&nbsp;SYNDROME.
</p>pharmachemm.com

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